Posters
Congratulations to the Poster Prize winners 2013:
1. Prize: Katrin Liffers (Hamburg) - Poster No. 46
2. Prize: Annegret Kathagen (Hamburg) - Poster No. 36
3. Prize: Felicitas Merz (Leipzig) - Poster No. 51
4. Prize: Irene Appoloni (Genova) - Poster No. 2
5. Prize: Roberta Galli (Dresden) - Poser No. 23
Poster size: 120 cm height and 100 cm width (maximum size).
Poster will hang during the entire meeting. The poster presenters are kindly requested to be at their poster during the poster sessions, i.e.
- Thursday, May 23, 2013: 15.25 - 16.00 and 17:20 - 17.50
- Friday, May 24, 2013: 10.00 - 10.40
List of Poster Presentations
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Antonietti, Patrick
Experimental Neurosurgery, Goethe University Hospital, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany, Antonietti@med.uni-frankfurt.de
KNOCKDOWN OF BAG3 REACTIVATES APOPTOTIC CELL DEATH TRIGGERED BY THE PAN BCL-2 INHIBITOR GOSSYPOL
Antonietti, P.; Rakel, S.; Voss, V; Kögel, D.
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Appolloni, Irene
IRCCS AOU San Martino-IST, L.go Rosanna Benzi 10, 16132 Genova, Italy, irene.appolloni@istge.it
CADHERINS SWITCH IN GLIOMAGENESIS
Appolloni, I.; Barilari, M.; Malatesta P.
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Bauer, Chris
Microdiscovery, , Marienburger Straße 1, 10405 Berlin, Germany, chris.bauer@microdiscovery.de
SYSTHERDB: A KNOWLEDGEBASE FOR BRAIN TUMOR SYSTEMS BIOLOGY
Bauer, C.; Glintschert, A.; Gruden, K; Schichor, C.; Or-Guil, M.; Selbig, J.; Schuchhardt, J.
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Bergström, Tobias
Department of Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 75185 Uppsala, Sweden, tobias.bergstrom@igp.uu.se
MAST CELLS ARE RECRUITED TO GLIOMA AND ORCHESTRATE CANCER CELL INVASION
Bergström, T.
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Bien-Möller, Sandra
University of Greifswald, Institute of Pharmacology, Felix-Hausdorff-Straße 3, 17487 Greifswald, Germany, sbien@uni-greifswalde.de
INHIBITION OF PIM1 KINASE RESULTS IN DECREASED GROWTH AND ENHANCED APOPTOSIS OF GLIOBLASTOMA CELLS
Bien-Möller, S.
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Brösicke, Nicole
Lehrstuhl für Zellmorphologie & molekulare Neurobiologie, Ruhr-Universität Bochum, Universitätsstr. 150, 44801 Bochum, Germany, Nicole.Broesicke@rub.de
NEW MONOLOVAL ANTIBODIES REVEAL A CLOSE ASSOCIATION OF TENASCIN-C WITH ANGIOGENESIS IN HUMAN GLIOMAS AND A POTENTIAL ROLE IN THE VASCULAR TUMOR STEM CELL NICHE
Brösicke, N.; Scheffler, B.; van Landeghem, F.; Faissner, A.
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Brucker, David
Zentrum für Neuropathologie, LMU München, Feodor-lynen Straße 23, 81377 München, Germany, david.brucker@med.uni-muenchen.de
INTRAVITAL IMAGING OF MICROGLIA/MACROPHAGE INTERACTIONS WITH HUMAN BRAIN TUMOR CELL LINES
Brucker, D ; von Baumgarten, L; Winkler, F; Herms,J.
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Busek, Petr
Laboratory of Cancer Cell Biology, Institute of Biochemistry and Experimental Oncology, 1st Faculty of Medicine, Charles University in Prague, Nemocnice 5, 12853 Prague, Czech Republic, busekpetr@seznam.cz
DIPEPTIDYL PEPTIDASE-IV IS EXPRESSED IN GLIOMA STEM-LIKE CELLS AND IS DOWNREGULATED DURING THEIR IN VITRO DIFFERENTIATION
Busek, P.; Sromova, L.; Hilser, M.; Krepela, E.; Sedo, A.
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Carro, Maria Stella
Neurosurgery, University of Freiburg, Breisacherstraße 64, 79106 Freiburg, Germany, maria.carro@uniklinik-freiburg.de
PTBP1-MEDIATED ABERRANT SPLICING OF A BRAIN-SPECIFIC EXON IN ANXA7 PROMOTES BRAIN TUMORIGENESIS
Carro, M.S.; Ferrarese, R; Bug, E; Bredel, M.
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Ciechomska, Iwona
Department of Cell Biology, Nencki Institute of Experimental Biology, Pasteur 3, 0 Warsaw, Poland, jcjech@nencki.gov.pl
GLIOMA STEM LIKE CELLS-ISOLATION, BIOLOGY AND DETERMINANTS OF CHEMORESISTANCE
Ciechomska, I.; Kocyk, M.; Kaminska, B.
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Denicolaï, Emilie
UMR911-CRO2, faculty of medicine “la Timone", 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France, emilie.denicolai@etu.univ-amu.fr
PROSCILLARIDIN A, A NEW DRUG FOR GLIOBLASTOMA TREATMENT?
Denicolaï, E.; Baeza-Kallee, N.; Tchoghandjian, A.; Jiguet Jiglaire, C.; Beclin, C.; Figarella-Branger, D.
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Dildar a Dzaye, Omar
Cellular Neurosciences group, MDC-Berlin Buch, Robert-Rössle-Str. 10, 13092 Berlin, Germany, omar.dzaye@mdc-berlin.de
GLIOMA-INITIATING CELLS (GIC) EXPLOIT GLIOMA ASSOCIATED MICROGLIA / MACROPHAGES (GAM) FOR INCREASED IL-6 SECRETION
Dildar a Dzaye, O., Hu, F., Synowitz, M., Wolf, S. A., and Kettenmann, H.
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Drachsler, Moritz
Molecular Neurobiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany, m.drachsler@dkfz-heidelberg.de
THE CD95 RECEPTOR IDENTIFIES GLIOBLASTOMA STEM CELLS
Drachsler, M.; Kleber, S.; Mateos, A.; Volk, K.; Tüttenberg, J.; Sykora, J.; Müller, W.; Synowitz, M.; Martin-Villalba, A.
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Eissler, Nina
Oncology-Pathology, Cancer Center Karolinska, Karolinska Institutet, CCK, R8:01, 17176 Stockholm, Sweden, nina.eissler@ki.se
THE ROLE OF STROMAL CELLS IN GLIOMA TUMOR GROWTH AND LOCAL INVASION
Eissler, N.; Sobocki, C.; Bolin, S.; Boije, M.; Sjöstedt, A.; Chuganova, E.; Swartling, F.; Uhrbom, L.; Rolny, C.
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Ellert-Miklaszewska, Aleksandra
Laboratory of Transcription Regulation, Nencki Institute of Experimental Biology PAS, Pasteur 3, 0 Warsawa, Poland, aellert@nencki.gov.pl
PRO-INVASIVE POLARIZATION OF MICROGLIA IN GLIOMAS DEPENDS ON TUMOR-DERIVED INTEGRIN LIGANDS
Ellert-Miklaszewska, A.; Kijewska, M.; Wisniewski, P.; Pszczolkowska, D.; Gerigk, M.; Przanowski, P.; Kaza, B.; Kaminska, B.
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Engel, Dorothee
Anatomy, University of Kiel, Olshausenstraße 40, 24098 Kiel, Germany, dorothee.engel@gmail.com
EMBRYONIC STEM CELL MARKERS IN HUMAN ASTROCYTOMAS
Engel, D.; Hattermann, K.; Ardabili, S.; Held-Feindt, J.; Mentlein, R.
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Eskilsson, Eskil
Biomedicine, University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway, eskil.eskilsson@biomed.uib.no
C-SRC EXPRESSION AND ACTIVATION PROMOTE GROWTH AND ANGIOGENESIS OF HUMAN GLIOBLASTOMA
Eskilsson, E.; Talasila, K. M.; Brekkå, N.; Lund-Johansen, M.; Bjerkvig, R.; Miletic, H.
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Euskirchen, Philipp
Dept. of Neurology, Charité Universitätsmedizin Berlin, Robert-Koch-Platz 4, AG Harms, Ebene 4, 10115 Berlin, Germany, philipp.euskirchen@charite.de
GENERATION OF A PATIENT-MATCHED GLIOBLASTOMA CELL LINE LIBRARY
Euskirchen, P.; Radke, J.; Nigro, J.; Miletic, H.; Koch, A.; Czabanka, M.; Dieterich, C. and Harms, C.
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Fedele, Vita
Neurooncology, Uniklinik Freiburg, Breisacherstraße 64, 79106 Freiburg, Germany, vita.fedele@uniklinik-freiburg.de
ROLE OF ZNF238 IN MESENCHYMAL GLIOBLASTOMA
Fedele, V.; Dai, F.; Bredel, M.; Carro, M.S.
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Fink, Matthias
University of Greifswald, Institute of Pharmacology, Felix-Hausdorff-Straße 3, 17487 Greifswald, Germany, Matthias-Fink@gmx.net
UPREGULATION OF THE CARNITINE TRANSPORTER OCTN2 IS ASSOCIATED WITH A POOR SURVIVAL OF PATIENTS WITH GLIOBLASTOMA MULTIFORME
Fink, M.A.
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Galli, Roberta
Medizinische Fakultät Carl Gustav Carus - Klinisches Sensoring und Monitoring, Technische Universität Dresden, Fetscherstraße 74, 1307 Dresden, Germany, Roberta.Galli@tu-dresden.de
MULTIMODAL NON-LINEAR OPTICAL MICROSCOPY (NLOM): A NEW TECHNIQUE FOR LABEL-FREE IMAGING OF BRAIN TUMORS
Galli, R.; Uckermann,O.; Tamosaityte, S.; Geiger, K. D.; Schackert, G.; Kirsch, M.; Koch, E.; Steiner, G.
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Gambini, Eleonora
DiMeS (Department of Experimental Medicine), IRCCS AOU San Martino – IST, L.go Rosanna Benzi 10, 16132 Genova, Italy, eleonora.gambini@gmail.com
TARGETING MALIGNANT GLIOMAS WITH ENGINEERED HERPES VIRUS
Gambini, E.; Reisoli, E.; Appolloni, I.; Gatta, V.; Menotti, L.; Malatesta, P.
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Geiger, Kathrin D.
Neuropathology/ Pathology, University hospital Dresden, Fetscherstraße 74, 1307 Dresden, Germany, kathrin.geiger@uniklinikum-dresden.de
EXPRESSION OF THE PROSTATE STEM CELL ANTIGEN (PSCA) IS ASSOCIATED WITH MALIGNANCE OF HUMAN MENIGIOMAS AND APPEARS TO BE MORE FREQUENTLY EXPRESSED IN PRIMARY MALIGNANT MENINGIOMAS
Geiger, K.D.; Stirnnagel, K.; Juratli, T.; Temme, A.; Schackert, G.
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Geßler, Florian
Klinik für Neurochirurgie, Universitätsklinikum Frankfurt am Main, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany, f.gessler@med.uni-frankfurt.de
BETA-ARRESTIN 1 IS A KEY PLAYER IN GLIOMA CELL MIGRATION AND INVASION AND REGULATED BY PP2A ACTIVITY
Geßler, F.; Dützmann, S.; Brauss, T.; Seifert, V.; Kögel, D.
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Grube, Susanne
Department of Neurosurgery, Jena University Hospital - Friedrich Schiller University Jena, Erlanger Allee 101, 7747 Jena, Germany, susanne.grube@med.uni-jena.de
ORGANOTYPIC SLICE CULTURES OF HUMAN GLIOMA TUMOR EXPLANTS AS A MODEL FOR THE INVESTIGATION OF THE EFFECTS OF FAS INHIBITION
Grube, S.; Freitag, D.; Ewald, C.; Kalff, R.; Walter, J.
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Hagel, Christian
Institute of Neuropathology, University Clinic Hamburg-Eppendorf, Martinistraße 52, 20251 Hamburg, Germany, hagel@uke.de
DIFFERENTIAL EXPRESSION OF GLIAL AND NEURONAL ANTIGENS IN SUPRA- AND INFRATENTORIAL PEDIATRIC EPENDYMOMAS
Hagel, C.; Treszl, A.; von Bueren, A.O.; Kordes, U.
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Hagemann, Carsten
Neurochirurgische Klinik und Poliklinik, Tumorbiologisches Labor, Universitätsklinikum Würzburg, Josef-Schneider-Straße 11, 97080 Würzburg, Germany, hagemann_c@klinik.uni-wuerzburg.de
CORRELATION OF MACC1 EXPRESSION WITH HUMAN MALIGNANT GLIOMA PROGRESSION AND PATIENTS PROGNOSIS
Hagemann, C.; Fuchs, S.; Monoranu, C. M.; Kessler, A. F.; Herrmann, P.; Smith, J.; Ernestus, R.-I.; Löhr, M.; Vince, G. H.; Stein, U.
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Henriksen, Michael
Health Science and Technology, Aalborg University, Frederik Bajers Vej 3B, 9220 Aalborg Ø, Denmark, michen@hst.aau.dk
DOWN-REGULATION OF FABP7 IN GLIOBLASTOMA PRIMARY CULTURES
Henriksen, M; Duroux, L; Pilgaard, L; Zachar, V; Duroux, M
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Herzog, Susann
University of Greifswald, Institute of Pharmacology, Felix-Hausdorff-Straße 3, 17487 Greifswald, Germany, herzogs@uni-greifswald.de
IMPACT OF PIM1 KINASE AS A NOVEL THERAPEUTIC TARGET IN GBM
Herzog, S.
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Hoornaert, Chloé
Laboratory of Experimental Hematology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium, Chloe.Hoornaert@ua.ac.be
TOWARDS VACCINATION-INDUCED MODULATION OF TUMOR-INFILTRATING IMMUNE CELLS IN THE GL261 GLIOMA MODEL
Hoornaert, C.; Le Blon, D.; De Vocht, N.; Daans, J.; Reekmans, K.; Berneman, Z.; Ponsaerts, P.
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Hu, Feng
Cellular Neurosciences, Max Delbrueck Center, Robert Roessle Str. 10, 13125 Berlin, Germany, hu.feng@mdc-berlin.de
MICROGLIAL/BRAIN MACROPHAGE TOLL-LIKE-RECEPTOR 2 SIGNALING PROMOTES GLIOMA EXPANSION
Hu, F., Vinnakota, K., Wolf, S., Kettenmann, H.
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Irschick, Regina
Division of Neuroanatomy, Medical University Innsbruck, Muellerstrasse 59, 6020 Innsbruck, Austria, Regina.Irschick@i-med.ac.at
FGFR1/FGF2 TRAFFICKING IN HUMAN GLIOMA CELLS
Irschick, R., Youssef, M., Karp, G., Trost. T., Claus, P., Klimaschewski, K.
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Karpel-Massler, Georg
Departement of Neurosurgery, University of Ulm Medical School, Albert-Einstein-Allee 23, 89081 Ulm, Germany, georg.karpel@uniklinik-ulm.de
MOLECULAR MECHANISMS MEDIATING THE SYNERGISTIC ANTIPROLIFERATIVE EFFECT OF ERLOTINIB AND NSC23766 ON GLIOBLASTOMA CELL LINES
Karpel-Massler, G.; Westhoff, M. A.; Dwucet, A.; Wirtz, C. R.; Debatin, K. M.; Halatsch, M. – E.
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Kathagen, Annegret
Neurosurgery, UKE, Martinistraße 52, 20246 Hamburg, Germany, A.Kathagen@uke.de
HYPOXIA AND OXYGENATION INDUCE A METABLOIC SWITCH BETWEEN THE PENTOSE PHOSPHATE PATHWAY AND GLYCOLYSIS IN GLIOMA STEM-LIKE CELLS
Kathagen, A.; Schulte, A.; Balcke, G.; Kuhl, C.; Günther, H.; Phillips, H.; Westphal, M.; Lamszus, K.
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Keßler, Almuth F.
Neurochirurgische Klinik und Poliklinik, Universitätsklinik Würzburg, Josef-Schneider-Straße 11, 97080 Würzburg, Germany, kessler.a@nch.uni-wuerzburg.de
THE MITOTIC CELL CYCLE CHECKPOINT OF GLIOBLASTOMA CELLS UNDER HYPOXIC CONDITIONS
Kessler, A.F.; Fett, S.; Monoranu, C.M.; Mühlhäußer, L.; Löhr, M.; Ernestus, R.-I.; Hagemann, C.
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Kleindienst, Andrea
Dept. of Neurosurgery, Klinikum Amberg, Univ. of Erlangen, Mariahilfbergweg 7, 92224 Amberg, Germany, andrea.kleindienst@uk-erlangen.de
LOCAL TREATMENT WITH OZONE/OXYGEN IN RECURRENT GLIOBLASTOMA RESULTS IN TUMOR CONTROL AT 6 MONTHS - A CASE REPORT
Megele, R.; Fischer von Weikersthal, L.; Fahrig, A.; Huber, F.; Engelbrecht, V.; Kleindienst, A.
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Kloss, Michal
Department of Cell Biology, Nencki Institute of Experimental Biology, 3 Pasteur Street, 0 Warszawa, Poland, m.kloss@nencki.gov.pl
REGULATION OF OSTEOPONTIN EXPRESSION IN GLIOMA
Kloss M., Kijewska M., Dabrowski M., Kaminska B.
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Kocyk, Marta
Cell Biology, Nencki Institute of Exprimental Bilogy, 3 Pauster Street, 0 Warsaw, Poland, mkocyk@nencki.gov.pl
INFILTRATING MICROGLIA SHOW DIFFERENT GENE EXPRESSION PROFILES IN LOW AND HIGH GRADE GLIOMAS
Kocyk, M.; Mieczkowski J.; Nauman P.; Tykocki T.; Kostkiewicz B.; Kotulska K.; Kaminska B.
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Kolb, Marlen
Universität Leipzig, Intitut für Biochemie Medizinische Fakultät, Johannisallee 30, 4103 Leipzig, Germany, marlen.kolb@medizin.uni-leipzig.de
A SPLICE VARIANT OF LRP1 – A NOVEL UBIQUITARY MARKER FOR CANCER DIAGNOSIS AND THERAPY
Kolb, M.; Trettner, S.; Büttner, S.; Engel, K.M.Y.; Seiboth, T.; Huse, K.; Birkenmeier, G.
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Kraus, Theo
Center for Neuropathology, Ludwig-Maximilians-University, Feodor-Lynen-Straße 23, 81377 Munich, Germany, theo.kraus@med.uni-muenchen.de
DYSREGULATION OF METHYLATION AND DEMETHYLATION PATHWAYS IN GLIOBLASTOMAS
Kraus T.F.J.; Greiner A.; Widmann D.; Kolck G.; Eigenbrod S.; Globisch D.; Wagner M.; Tonn JC.; Carell T.; Kretzschmar H.A..
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Krombholz, Alina-Sophie
Department of Neurosurgery, Jena University Hostipal - Friedrich Schiller University Jena, Erlanger Allee 101, 7747 Jena, Germany, alina-sophie.krombholz@uni-jena.de
MTOR-INHIBITION AND INTERRUPTION OF PI3K/AKT SIGNALLING DECREASES PROLIFERATION AND INDUCES APOPTOSIS IN HUMAN MENINGIOMA CELLS
Krombholz, A.-S.; Grube, S.; Freitag, D.; Ewald, C.; Kalff, R.; Walter, J.
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Ku, Min-Chi
Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany, min-chi.ku@mdc-berlin.de
MONITORING DENDRITIC CELLS AS IMMUNOTHERAPIES IN HIGH GRADE GLIOMA
Ku, M. C.; Günther, M.; Waiczies, H.; Pohlmann, A.; Lepore, S.; Drechsler, S.; Wolf, S.; Kettenmann, H.; Waiczies, S.; Niendorf
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Kübler, Ulrich
Kübler GmbH, Siebertstraße 6, 81675 München, Germany, info@kueblergmbh.com
ISOLATION AND MOLECULAR CHARACTERIZATION OF GLIOMA STEM CELLS
Kübler, U.; Schnepel, J.
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Kundu, Soumi
Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, Rudbecklaboratoriet, 0 Uppsala, Sweden, soumi.kundu@igp.uu.se
HEPARANASE IS EXPRESSED IN HUMAN GLIOBLASTOMA AND REGULATES GROWTH OF MOUSE MALIGNANT GLIOMA
Kundu, S.; Xiong, A.; Zhang, L.; Forsberg, M.; Dimberg, A.; Li, J-P.; Forsberg-Nilsson, K.
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Liffers, Katrin
Department for Neurosurgery, Laboratory for Brain Tumor Biology, University Hospital Hamburg-Eppendorf, Institute for Tumor Biology, Grandweg 124, 22529 Hamburg, Germany, k.liffers@uke.de
DETERMINING MOLECULAR PRINCIPLES OF TUMOR INITIATION OF EGFR-AMPLIFIED GLIOBLASTOMA BY MULTICOLOR LABELING OF INDIVIDUAL CELLS
Liffers, K.; Kolbe, K.; Riecken, K.; Fehse, B.; Westphal, M.; Lamszus, K.; Schulte, A.
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Markovic, Darko
Department of Neurosurgery, Helios Klinikum Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany, darko.markovic@helios-kliniken.de
TREATMENT WITH MINOCYCLINE AND p38MAPK BLOCKER REDUCE GLIOMA-INDUCED MATRIX METALLPROTEASE (MMP) 9 OVEREXPRESSION IN MICROGLIA
Markovic, D.S.;Min-Chi, K.; Kiwit, J.; Kettenmann, H.
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Mercurio, Sandy
UMR911-CRO2, 27 Bd Jean MOULIN, faculty of medicine “la Timone”, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France, sandy.mercurio@univ-amu.fr
EVIDENCE FOR NEW TARGETS AND SYNERGISTIC EFFECT OF METRONOMIC CELECOXIB/FLUVASTATIN COMBINATION IN PILOCYTIC ASTROCYTOMA
Mercurio, S ; Padovani, L ; Colin, C ; Carré, M ; Scavarda, D ; Lambert, S ; Baeza-Kallee, N ; Fernandez, C ; Chappé, C ; Lena,
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Merz, Felicitas
Institute of Anatomy, University of Leipzig, Liebigstraße 13, 4103 Leipzig, Germany, felicitas.merz@medizin.uni-leipzig.de
ORGANOTYPIC SLICE CULTURES OF HUMAN GLIOBLASTOMA RESPOND INDIVIDUALLY TO RADIO- AND CHEMOTHERAPEUTIC TREATMENT
Merz, F.; Gaunitz, F.; Renner, C.; Meixensberger, J.; Gutenberg, A.; Giese, A.; Schaefer, M.; Bauer, M.; Taucher-Scholz, G.; Durante, M.; Bechmann, I.
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Miletic, Hrvoje
Pathology, Haukeland University Hospital, Jonas Lies vei 65, 5021 Bergen, Norway, hrvoje.miletic@biomed.uib.no
EGFR WILD-TYPE AMPLIFICATION AND ACTIVATION PROMOTE INVASION AND DEVELOPMENT OF GLIOBLASTOMA INDEPENDENT OF ANGIOGENESIS
Miletic, H; Talasila, KM; Soentgerath, A; Euskirchen, P; Rosland, GV; Wang, J; Eskilsson, E; Stieber, D; Enger, P; Bjerkvig, R
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Mortensen, Joachim Høg
Biomedicine, Aalborg University, Samsøgade 23 st. tv., 0 Aalborg, Denmark, joachim.hoeg.mortensen@gmail.com
CRIPTO-1 IS DIFFERENTIALLY EXPRESSED IN GLIOBLASTOMA AND RESIDES IN THE VASCULAR NICHE
Mortensen, J.H.; Pilgaard, L.; Henriksen, M.; Olsen, P.; Sørensen, P.; Agger, R.; Vyberg, M.; Moos, T.; Zachar, V.; Duroux, M.;
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Müller, Nadja
Neurochirurgische Forschung, Universitätsklinikum Carl-Gustav-Carus der TU Dresden, Fetscherstraße 74, 1307 Dresden, Germany, nadja.mueller@uniklinikum-dresden.de
TARGETING EGFRVIII-POSITIVE GLIOMA CELLS USING A NOVEL NK CELL CHIMERIC ANTIGEN RECEPTOR CONSISTING OF DAP12 AND SCFV-(MR1.1)
Müller, N.; Cartellieri, M.; Schackert, G.; Temme, A.
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Narasimhaiah, Deepti
Laboratory of Pathology, Université catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium, deepti.narasimhaiah@uclouvain.be
FAMILIAL PRESENTATION OF A GRANULAR CELL ASTROCYTOMA AND AN OLIGODENDROGLIOMA
Narasimhaiah, D.; Amyere, M.; Janin, N.; Raftopoulos, C.; Vikkula, M.; Godfraind, C.
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Pavlakis, Evangelos
RG for Molecular Developmental Neurobiology, Max Planck Inst. for biophysical Chemistry, Am Fassberg 11, 37077 Goettingen, Germany, epavlak@mpibpg.mpg.de
DIFFERENTIAL REGULATION OF PAX6 AND PAX6-5A ISOFORMS BY mIRNA CLUSTER MIR-183-96-182 IN GLIOBLASTOMA MULTIFORM
Pavlakis, E.; Tonchev, A.; Stoykova, A.
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Pellegatta, Serena
Molecular Neuro-Oncology, FONDAZIONE IRCCS Istituto Neurologico C. Besta, Via Celoria 11, 20133 Milan, Italy, serenapellegatta@gmail.com
THE GLUTAMATE ASPARTATE TRANSPORTER GLAST PLAYS A KEY ROLE IN GLIOBLASTOMA INVASION
Pellegatta, S.; Poliani, PL.; Cantini, G.; Pisati, F.; Finocchiaro, G.
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Pinet, Sandra
EA3842 Homéostasie cellulaire et pathologies, Faculté de Médecine / Faculté des sciences et Techniques, 2 rue du Docteur Marcland, 87025 Limoges, France, sandra.pinet@etu.unilim.fr
HYPOXIA MODULATES NEUROTROPHIC FACTORS EXPRESSION IN HUMAN GLIOBLASTOMA CELL LINES.
Pinet, S.; Bessette, B.; Lacroix, A.; Cheray, M.; Couturaud, B.; Jauberteau, M.O.; Battu, S.; Lalloué, F.
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Røsland, Gro
Dep.of Biomedicine, University of Bergen, Jonas Lies Vei 91, 5009 Bergen, Norway, gro.rosland@biomed.uib.no
DISTINCT FUNCTIONAL ROLES OF WILD-TYPE EGFR AND ITS MUTANT EGFRVIII IN GLIOBLASTOMA DEVELOPMENT
Røsland,GV.; Talasila KM.;Eskilsson,E.;Jahedi,R.;Stieber,D.;Azuaje,F.;Varughese,J.;Niclou,S.;Bjerkvig,R.;Miletic,H.
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Radke, Josefine
Neuropathology, Charité, Virchowweg 15, 10117 Berlin, Germany, josefine.radke@charite.de
AKT AND C-MYC INDUCE STEM-CELL MARKERS IN MATURE PRIMARY P53-/- ASTROCYTES AND RENDER THESE CELLS GLIOMAGENIC IN THE BRAIN OF IMMUNOCOMPETENT MICE
Radke, J.; Bortolussi, G.; Pagenstecher, A.
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Rakel, Stefanie
Experimental Neurosurgery, Center of Neurology and Neurosurgery, Heinrich-Hoffmann Straße 7, 60528 Frankfurt am Main, Germany, stefanie.rakel@kgu.de
DYNAMIC CHANGES IN THE INTERACTOMES OF BCL-2 FAMILY MEMBERS DURING AUTOPHAGIC CELL DEATH
Rakel, S.; Behrends, C.; Voss, V; Seifert, V.; Kögel, D.
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Rasmussen, Rikke Darling
Genome Integrity Group, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark, rikras@cancer.dk
THERAPEUTIC TARGETING OF CONSTITUTIVE PARP ACTIVATION COMPROMISES STEM CELL PHENOTYPE AND SURVIVAL OF GLIOBLASTOMA INITIATING CELLS
Rasmussen, R. D.; Hamerlik, P.; Venere, M.; Wu, Q.; Song, L. A.; Vasanji, A.; Tenley, N.; Flavahan, W.; Anita B.
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Reinartz, Roman
Institute of Reconstructive Neurobiology, Sigmund Freud Strasse 25, 53127 Bonn, Germany, roman.reinartz@uni-bonn.de
COMPARATIVE ANALYSIS OF CLONAL SUBCULTURES FROM HUMAN GLIOBLASTOMA WITH MOSAIC AMPLIFICATION OF CHR. 4q12 ALLOWS INVESTIGATION OF PDGFRA/KIT FUNCTION ON A SIMILAR GENETIC BACKGROUND
Reinartz, R.; Wieland, A.; Trageser, D.; Keller, M.; Simon, M.; Schildhaus, H.U.; Brüstle, O.; Glas, M.; Scheffler, B.
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Rosenfeld, Steven
Cancer Biology, Cleveland Clinic Foundation, 9500 Euclid Avenue, NB40, 44195 Cleveland, OHIO, USA, rosenfs@ccf.org
DIRECT INHIBITION OF MYOSIN II EFFECTIVELY BLOCKS GLIOMA INVASION IN THE PRESENCE OF MULTIPLE MOTOGENS
Rosenfeld, S.S; Ivkovic, S; Beadle, C; Noticewala, S; Massey, SC; Swanson, K.R.; Toro, L.N.; Bresnick, A.R.; and Canoll, P.C.
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Schulte, Alexander
Neurosurgery, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 22769 Hamburg, Germany, aschulte@uke.de
PI3KP110DELTA IS CRUCIAL FOR EGFRVIII-MEDIATED ERLOTINIB TOLERANCE IN AN EGFR-AMPLIFIED GLIOBLASTOMA MODEL
Schulte, A.; Liffers, K.; Merlo, A.; Riethdorf, S.; Kolbe, K.; Westphal, M.; Lamszus, K.
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Sielska, Malgorzata
Department of Cell Biology, Nencki Institute of Experimental Biology, 3 Pasteur Street, 0 Warsaw, Poland, m.sielska@nencki.gov.pl
TUMOR-DERIVED GM-CSF DRIVES MICROGLIA/MACROPHAGE INFILTRATION AND GLIOMA PROGRESSION
Sielska, M.; Grzeganek, D.; Przanowski, P.; Kocyk, M.; Maleszewska, M.; Kaminska, B.
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Sreedharan, Smitha
Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 0 Uppsala, Sweden, smitha14@gmail.com
SIGNIFICANCE OF CELL OF ORIGIN IN PEDIATRIC GLIOMA
Sreedharan, S.; Caglayan, D.; Uhrbom L
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Tchoghandjian, Aurélie
UMR911-C RO2, Faculté de Médecine la Timone, 27 bd jean Moulin, 13385 Marseille Cedex 5, France, aurelie.tchoghandjian@univ-amu.fr
SMAC MIMETIC PROMOTES GLIOBLASTOMA CANCER STEM-LIKE CELL DIFFERENTIATION BY ACTIVATIONG NF-MYB
Tchoghandjian, A.; Jennewein, C.; Eckhardt, I.; Momma, S.; Figarella-Branger, D.; Fulda, S.
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Tietz, Stephanie
Department of Neurosurgery, Jena University Hospital - Friedrich Schiller University Jena, Erlanger Allee 101, 7747 Jena, Germany, stephanie.tietz@uni-jena.de
INHIBITION OF MTOR AND ITS PATHWAY INDUCES APOPTOSIS AND DECREASES PROLIFERATION IN HUMAN GLIOBLASTOMA CELLS
Tietz, S.; Grube, S.; Freitag, D.; Ewald, C.; Kalff, R.; Walter, J.
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Timmer, Marco
Neurosurgery, , Kerpener Straße 62, 50937 Köln, Germany, marco.timmer@uk-koeln.de
EXPRESSION PROFILE OF DRUG-METABOLIZING AND DRUG-RESISTANCE GENES IN PRIMARY, SECONDARY AND RECURRENT HUMAN GLIOMAS
Timmer, M.; Stavrinou, P.; Röhn, G.; Koch, A.; Goldbrunner, R.
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Uckermann, Ortrud
Klinik und Poliklinik für Neurochirurgie, Uniklinikum Dresden, Fetscherstraße 74, 1307 Dresden, Germany, Ortrud.Uckermann@uniklinikum-dresden.de
ASSESSMENT OF CARS-MICROSCOPY FOR LABEL-FREE DELINEATION OF GLIOBLASTOMA AND BRAIN METASTASES IN A MOUSE MODEL
Uckermann, O.; Galli, R.; Tamosaityte, S.; Geiger, K. D.; Schackert, G.; Steiner, G.; Kirsch, M.
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Vomelová, Ivana
Laboratory of Cancer Cell Biology, Institute of Biochemistry and Experimental On, 1st Faculty of Medicine, Charles University in Prague, U Nemocnice 5, 12853 Prague 2, Czech Republic, vomelova.ivana@email.cz
HETEROGENEITY OF DIPEPTIDYL PEPTIDASE-IV AND FIBROBLAST ACTIVATION PROTEIN IN GLIOMA PRIMARY CELLS AND CELL LINES
Sedo, A.; Vomelová, I.; Fejfarová, E.
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Wicher, Grzegorz
Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 0 Uppsala, Sweden, Grzegorz.Wicher@igp.uu.se
IL-33 IN THE HEALTHY AND PATHOLOGICAL BRAIN.
Wicher, G.; Wallenquist, U.; Enoksson, M.; Husic, E.; Fuchs, B.; Dimberg. A.; Hillered, L.; Nilsson, G.; Forsberg-Nilsson, K.
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Xie, Yuan
Uppsala University, Immunology, Genetics and Pathology, Dag Hammarskjölds v 20, 75185 Uppsala, Sweden, yuan.xie@igp.uu.se
GLIOBLASTOMA CELL OF ORIGIN AS A BASIS FOR SUBCLASSIFICATION, TARGET IDENTIFICATION AND DRUG SCREENING
Xie,Y.
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Xiong, Anqi
Dept. of immunology, genetics and pathology, Uppsala, Dag Hammarskjölds v 20, 75185 Uppsala, Sweden, anqi.xiong@igp.uu.se
NUCLEAR RECEPTOR BINDING PROTEIN 2 (NRBP2) IN NEURAL DIFFERENTIATION AND BRAIN TUMORS
Xiong, A.; Larsson, J.; Alemayehu, G.; Olofsson, T.; Engström, U.; Forsberg-Nilsson, K.
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Xu, Li-Xin
Department of Neurosurgery, University of Leipzig, Johannisallee 30, 04103 Leipzig, Germany, lixin.xv@gmail.com
GENETIC ANALYSES OF THREE GANGLIOGLIOMAS USING GTG-BANDING, SKY, AND GENOME-WIDE HIGH RESOLUTION SNP- ARRAY
Xu, L.X.; Holland, H.; Ahnert, P.; Koschny, R.; Bauer, M.; Schober, R.; Kirsten, H.; Meixensberger, J.; Krupp, W.
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Zamykal, Martin
Laboratory of Brain Tumour Biology, Dpt. of Neurosurgery, University Medical Center Hamburg-Eppendorf, Isebekstraße 17, 22769 Hamburg, Germany, m.zamykal@uke.de
IGF-1R-BLOCKADE INHIBITS TUMOR GROWTH OF GLIOMA STEM-LIKE CELLS
Zamykal, M.; Martens, T.; Westphal, M.; Lamszus, K.
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